abstract：:Increased erythrocyte (RBC) sodium-lithium (Na-Li) counter transport (CT) has been reported to be a genetic marker for essential hypertension (EHT). In addition, increased RBC Na-Li CT has been demonstrated in insulin-dependent diabetic (IDDM) patients with nephropathy, indicating that a predisposition to hypertension...

journal_title：Diabetes research and clinical practice

authors： Senda T,Serizawa N,Negishi K,Katayama S

更新日期：1996-03-01 00:00:00

abstract：:High pressures on the soles of the feet of diabetic patients cause plantar ulcerations, and reduction of this pressure is important in the treatment and prevention of such ulcers. The effects of foot orthoses on the distribution of plantar pressures were investigated using a pressure-sensitive insole containing 960 se...

journal_title：Diabetes research and clinical practice

authors： Kato H,Takada T,Kawamura T,Hotta N,Torii S

更新日期：1996-03-01 00:00:00

abstract：:Abdominal obesity has emerged as a strong and independent predictor for non-insulin dependent diabetes mellitus (NIDDM). Adiposity located centrally in the abdominal region, and particularly visceral as opposed to subcutaneous fat, is also distinctly associated with hyperlipidemia, compared with generalized distributi...

journal_title：Diabetes research and clinical practice

authors： Kissebah AH

更新日期：1996-02-01 00:00:00

abstract：:Experimental data support a role for insulin and insulin-like growth factor-I (IGF-I) in the pathophysiology of vascular complications in diabetes. Clinical data for both hormones are less convincing, mainly because the various studies vary in methodologies, sample sizes, and populations. So far, by epidemiological me...

journal_title：Diabetes research and clinical practice

authors： Göke B,Fehmann HC

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:To determine if uncooked cornstarch, as part of the evening snack, can avert nocturnal hypoglycemia in type 1 diabetes. RESEARCH DESIGN AND METHODS:Fifty-one campers and counselors at the American Diabetes Association Camp in San Bernardino, CA were randomly assigned to receive 5 g of uncooked cornstarch as ...

journal_title：Diabetes research and clinical practice

authors： Kaufman FR,Halvorson M,Kaufman ND

更新日期：1995-12-01 00:00:00

abstract：:Considering the nervous system as a unit, it might be expected that diabetic patients with autonomic neuropathy could have a central abnormality expressed as cognitive dysfunction. To determine whether autonomic neuropathy is independently associated with cognitive dysfunction, we studied a cross-section of 20 non-ins...

journal_title：Diabetes research and clinical practice

authors： Zaslavsky LM,Gross JL,Chaves ML,Machado R

更新日期：1995-11-01 00:00:00

abstract：:To elucidate the relationship between carnitine metabolism and plasma ketone body concentrations in moderately obese patients with mild glucose intolerance, the ketone body and carnitine levels in the basal state were determined in 72 obese patients: 20 with normal glucose tolerance (NGT), 29 with impaired glucose tol...

journal_title：Diabetes research and clinical practice

authors： Inokuchi T,Imamura K,Nomura K,Nomoto K,Isogai S

更新日期：1995-10-01 00:00:00

abstract：:We retrospectively analyzed the courses of 37 non-insulin dependent diabetics (hemodialyzed:HD group) with end-stage renal disease (ESRD), to identify factors predisposing to renal failure. The factors analyzed were: diabetic (non-proliferative and proliferative) retinopathy, family histories of diabetes and hypertens...

journal_title：Diabetes research and clinical practice

authors： Takei I,Yamauchi A,Nakamoto S,Suzuki H,Saruta T

更新日期：1995-09-01 00:00:00

abstract：:The treatment of Type II diabetes (NIDDM) includes an appropriate diet and prudent exercise program. If these measures are insufficient to control the blood sugar, oral agents (sulphonylureas or biguanides) or insulin are added to the therapeutic regimen. Although the diet prescription has undergone some changes and r...

journal_title：Diabetes research and clinical practice

authors： Josse RG

更新日期：1995-08-01 00:00:00

abstract：:Potassium (K) channels regulate cellular excitability. Their opening hyperpolarises the membrane potential and induces quiescence whereas their closure produces depolarisation and excitation. One K-channel superfamily includes the delayed rectifier (KV), the A-type (KA) and the large conductance, Ca-sensitive (BKCa) c...

journal_title：Diabetes research and clinical practice

authors： Edwards G,Weston AH

更新日期：1995-08-01 00:00:00

abstract：:The aim of this study was to examine distinctive clinical characteristics of non-insulin dependent diabetes mellitus (NIDDM) patients in Kuwait including mode of presentation at diagnosis, family history of diabetes, therapeutic management and response to treatment. We studied 3299 Kuwaiti patients (1454 male (M) and ...

journal_title：Diabetes research and clinical practice

authors： Abdella NA,Khogali MM,Salman AD,Ghuneimi SA,Bajaj JS

更新日期：1995-08-01 00:00:00

abstract：:To clarify the diagnostic relevance of urinary type IV collagen (IV-C) and laminin in diabetic nephropathy, the excretion of these basement membrane proteins were determined by enzyme immunoassay in 172 non-insulin-dependent diabetic patients with different grades of nephropathy and 64 non-diabetic control subjects, a...

journal_title：Diabetes research and clinical practice

authors： Banu N,Hara H,Okamura M,Egusa G,Yamakido M

更新日期：1995-07-01 00:00:00

abstract：:A 44-year-old woman with diabetes mellitus, cardiomyopathy, and a mitochondrial gene mutation, was reported. She was diagnosed as having diabetes at 33 years of age and was treated with insulin. However, she stopped treatment 6 months later and had no medical care until she developed diabetic ketoacidosis at 41 years ...

journal_title：Diabetes research and clinical practice

authors： Kitaoka H,Kameoka K,Suzuki Y,Sasaki E,Majima M,Takada K,Katagiri H,Oka Y,Ohsawa N

更新日期：1995-06-01 00:00:00

abstract：:A transient rise in hepatic glucose production (HGP) after an oral glucosa load has been reported in some insulin-resistant states such as in obese fa/fa Zucker rats. The aim of this study was to determine whether this rise in HGP also occurs in subjects with established non-insulin-dependent diabetes mellitus (NIDDM)...

journal_title：Diabetes research and clinical practice

authors： Thorburn A,Litchfield A,Fabris S,Proietto J

更新日期：1995-05-01 00:00:00

abstract：:Dietary cod-liver oil containing eicosapentaenoic acid is effective on microvascular albumin leakage in diabetic patients with albuminuria. We determined the long-term effects of oral pure eicosapentaenoic acid ethyl (EPA-E: 900 mg/day) administration on diabetic nephropathy in non-insulin dependent diabetic (NIDDM) p...

journal_title：Diabetes research and clinical practice

authors： Shimizu H,Ohtani K,Tanaka Y,Sato N,Mori M,Shimomura Y

更新日期：1995-04-01 00:00:00

abstract：:The aim of our study was to evaluate the efficiency of an individual intensive educational control program on improving the metabolic control of insulin-dependent diabetic patients at short- and long-term follow-up. Fifteen insulin-dependent diabetic subjects with poor metabolic control (hemoglobin A1c > 9%) were incl...

journal_title：Diabetes research and clinical practice

authors： Conget I,Jansá M,Vidal M,Vidal J,Manzanares JM,Gomis R

更新日期：1995-03-01 00:00:00

abstract：:The exocrine and endocrine pathophysiology of chronic calcific pancreatitis of the tropics (CCPT) remains elusive. The objective of this study was to evaluate the spectrum and correlates of the exocrine and endocrine pancreatic dysfunction in CCPT. Thirty-seven consecutive patients with a clinico-radiological diagnosi...

journal_title：Diabetes research and clinical practice

authors： Sidhu SS,Shah P,Prasanna BM,Srikanta SS,Tandon RK

更新日期：1995-02-01 00:00:00

abstract：:We assessed the effect of CS-045, a new hypoglycemic agent, on B-cell function in partially pancreatectomized rats. At the age of 4 weeks, male Wistar rats were subjected to 90% pancreatectomy (Px). For 2 weeks starting at 6 weeks after surgery the Px rats were treated with CS-045 (CS rats) mixed with chow pellets in ...

journal_title：Diabetes research and clinical practice

authors： Inoue Y,Tanigawa K,Nakamura S,Xu G,Kawaguchi M,Kato Y,Tamura K

更新日期：1995-01-01 00:00:00

abstract：:The purpose of this study was: (1) to record GP opinions, practices and outcomes for the care of Type 2 Diabetes Mellitus (DM2), (2) compare practice facilities and process of care with a criterion of recommended competent care and (3) determine if there were any differences between vocationally registered and non-voc...

journal_title：Diabetes research and clinical practice

authors： Kamien M,Ward AM,Mansfield F,Fatovich B,Mather C,Anstey K

更新日期：1994-12-31 00:00:00

abstract：:Serum insulin 1 h post-glucose load is examined in this prospective study of 2971 Caucasoid subjects aged > 20 years in 1966 and followed to 1989. The serum insulin levels as a continuous variable show no significant linear association with coronary heart disease (CHD) deaths in either sex after accounting for age by ...

journal_title：Diabetes research and clinical practice

authors： Welborn TA,Knuiman MW,Ward N,Whittall DE

更新日期：1994-11-01 00:00:00

abstract：:Insulin (immunoreactive insulin, IRI) response during a 100 g oral glucose tolerance test was studied in a large number of patients with definite diabetes, equivocal diabetes, and other pathological states causing glucose intolerance. Definite diabetes was diagnosed in patients with overt fasting hyperglycemia. Once t...

journal_title：Diabetes research and clinical practice

authors： Kosaka K,Kuzuya T,Hagura R

更新日期：1994-10-01 00:00:00

abstract：:In November 1990, we carried out a survey of chronic complications of diabetes in more than 2000 diabetic patients who were seen on one day in 35 medical institutions including university hospitals, other hospitals and small clinics. More than 60% were aged 55-74 years. About 7% of patients had IDDM. Hypertension was ...

journal_title：Diabetes research and clinical practice

authors： Kuzuya T,Akanuma Y,Akazawa Y,Uehata T

更新日期：1994-10-01 00:00:00

abstract：:Well-organized medical insurance systems cover all medical fees for diabetes mellitus, and diabetics can visit doctors quite freely in Japan. Also insulin therapy by self-injection became legal and covered by health insurance after 1981 in this country. Despite such good conditions for the patients, there are some pro...

journal_title：Diabetes research and clinical practice

authors： Hirata Y

更新日期：1994-10-01 00:00:00

abstract：:The first summer camp in Japan was held at a site near Tokyo in 1963. The guide book was edited by Japan Diabetes Society in 1984. In 1992, 1012 children with diabetes participated at 36 sites all across Japan. The programme is characterized by the smooth combination between education for the children and their experi...

journal_title：Diabetes research and clinical practice

authors： Mimura G

更新日期：1994-10-01 00:00:00

abstract：:The World Health Organization (WHO) has a section for non-communicable diseases, where the public health problems related to diabetes are treated. The WHO has cooperated with the International Diabetes Federation for many years. The classification of diabetes and diagnostic criteria proposed by its committee is now wi...

journal_title：Diabetes research and clinical practice

authors： Akazawa Y

更新日期：1994-10-01 00:00:00

abstract：:IDDM is known to be a heterogeneous disease which is frequently complicated with other autoimmune diseases (AID). We previously reported that IDDM patients with AID were characterized by late onset of diabetes, persistent ICA-positivity and increased association with DR9, while those without AID were characterized by ...

journal_title：Diabetes research and clinical practice

authors： Akawaza S,Kawasaki E,Yano M,Abiru N,Yamaguchi Y,Nagataki S

更新日期：1994-10-01 00:00:00

abstract：:Abnormalities of pulmonary function tests have been described in type 1 (insulin-dependent) diabetes mellitus (IDDM). To better characterise such abnormalities and to verify whether these latter are associated with the presence of diabetic microvascular disease we compared 23 non-smoking patients who had IDDM with 24 ...

journal_title：Diabetes research and clinical practice

authors： Innocenti F,Fabbri A,Anichini R,Tuci S,Pettinà G,Vannucci F,De Giorgio LA,Seghieri G

更新日期：1994-10-01 00:00:00

abstract：:Seventy-eight non-randomized patients with IDDM, aged 33.8 +/- 9.6 years (mean +/- S.D.), with a duration of diabetes of 16.6 +/- 9.5 years and a HbA1c level of 8.0% +/- 1.5 at baseline were included in the study. The effects of a change from a 3-dose insulin regimen using conventional syringes to a treatment mode usi...

journal_title：Diabetes research and clinical practice

authors： Karlson B,Agardh CD

更新日期：1994-09-01 00:00:00

abstract：:Since normal reference values change with age in some clinical parameters, we measured the plasma levels of 1,5-anhydroglucitol (AG), a new marker of glycemic control in diabetes mellitus, in healthy subjects and in rats. Our results showed a significantly negative correlation of the marker with age in humans and that...

journal_title：Diabetes research and clinical practice

authors： Funasako M,Taniji M,Fujimoto K,Ohata M,Higashimoto Y,Uetani K,Suruda T,Nakai S,Fujimoto H,Sakagami Y

更新日期：1994-08-01 00:00:00

abstract：:We investigated the follow-up status and prognosis of 109 patients with non-insulin-dependent diabetes mellitus aged from 10 to 19 years old (66 males and 43 females). Patients who had not attended hospital for at least 20 months up to the end of September 1990 were regarded as defaulters, and were surveyed by questio...

journal_title：Diabetes research and clinical practice

authors： Kawahara R,Amemiya T,Yoshino M,Miyamae M,Sasamoto K,Omori Y

更新日期：1994-07-01 00:00:00

abstract：:The Japan Diabetes Society (JDS) conducted a multicenter study on the immunogenetics of insulin-dependent diabetes mellitus (IDDM) among Japanese. The previous report of the JDS study described HLA types and other immunogenetic markers in Japanese patients with IDDM. In the present report, the autoimmunity of Japanese...

journal_title：Diabetes research and clinical practice

authors： Kida K,Mimura G,Kobayashi T,Matsuura N,Toyota T,Kitagawa T,Hibi I,Ikeda Y,Tuchida I,Kuzuya H

更新日期：1994-04-01 00:00:00

abstract：:There is a growing body of evidence that the insulin-like growth factors (IGF-I and IGF-II) are dynamically involved in the regulation of glucose homeostasis, with one of their binding proteins, IGFBP-1, playing a counterregulatory role. The IGFs are structurally and functionally related to insulin and in the circulat...

journal_title：Diabetes research and clinical practice

authors： Lewitt MS

更新日期：1994-02-01 00:00:00

abstract：:We examined the effect of aldehyde-modified matrix macromolecules on mesangial cell function in vitro, using incubated rat glomerular mesangial cells. Laminin and fibronectin were modified by incubation for 24 h with 50 mM glycolaldehyde (GA), a highly reactive cross-linking glycation product, with or without equimola...

journal_title：Diabetes research and clinical practice

authors： Hasegawa G,Nakano K,Tsutsumi Y,Kondo M

更新日期：1994-02-01 00:00:00

abstract：:Since Hirata et al. first reported a patient with insulin autoimmune syndrome in 1970, 197 cases have been reported in Japan as of December, 1992. The clinical profiles of these 197 cases were as follows; the peak age at onset was 60-69 years and peak duration of hypoglycemic attacks was more than 1 and less than 3 mo...

journal_title：Diabetes research and clinical practice

authors： Uchigata Y,Eguchi Y,Takayama-Hasumi S,Omori Y

更新日期：1994-01-01 00:00:00

abstract：:Urinary bladder dysfunction was investigated in spontaneously diabetic Chinese hamsters of the Asahikawa colony (CHAD). The wet weight of the urinary bladder was significantly increased in CHAD when compared with non-diabetic controls. In response to continuous infusion of physiological saline into the bladder under a...

journal_title：Diabetes research and clinical practice

authors： Itoh H,Morikawa A,Makino I

更新日期：1994-01-01 00:00:00

abstract：:We examined the covariability of subclinical albuminuria in a cohort of 160 insulin-dependent diabetics who underwent simultaneous measurements of overnight urinary albumin excretion rate (UAV) and several clinical variables on 7 occasions over a period of 18 months. After allowing for within-patient correlation betwe...

journal_title：Diabetes research and clinical practice

authors： Watts GF,Taub NA,Mazurkiewicz J,Shaw KM

更新日期：1993-08-01 00:00:00

abstract：:During the period from 1 June 1984 to 1 June 1991, 988 pregnant diabetic patients were treated by a team of physicians and obstetricians in Benghazi Diabetic Clinic. Twelve patients were insulin-dependent (type 1) and 976 patients were non-insulin-dependent (type 2). Ninety patients were diagnosed for the first time d...

journal_title：Diabetes research and clinical practice

authors： Kadiki OA,Reddy MR,Sahli MA,Shawar H,Rao S

更新日期：1993-07-01 00:00:00

abstract：:We analysed blood insulin and glucose concentrations before and during frequently sampled intravenous glucose tolerance tests (FSIGT) in 2 groups of Nigerian subjects: (A) Control group (n = 18), without a positive family history of diabetes mellitus, and (B) Experimental group (n = 16), comprising age-, sex- and body...

journal_title：Diabetes research and clinical practice

authors： Ezenwaka CE,Akanji AO,Osei K,Adejuwon CA,O'Dorisio TM,Cottrell DA,Akinlade KS

更新日期：1993-06-01 00:00:00

abstract：:The insulin sensitivity of intermediary metabolism was studied in 8 non-obese men with well-controlled diet-treated non-insulin dependent diabetes (NIDDM) using a low dose incremental insulin infusion (basal, 0.005 and 0.01 U/kg h-1). Results were compared to 8 healthy male control subjects matched (NIDDM vs. controls...

journal_title：Diabetes research and clinical practice

authors： Singh BM,Krentz AJ,Nattrass M

更新日期：1993-04-01 00:00:00

abstract：:Normoalbuminuric insulin-dependent diabetic (IDDM) patients may present higher rates of urinary albumin excretion after submaximal exercise at a standard intensity. To evaluate whether the urinary albumin excretion of IDDM patients is increased after maximal and submaximal exercise when exercise intensities are adjust...

journal_title：Diabetes research and clinical practice

authors： Bertoluci MC,Friedman G,Schaan BD,Ribeiro JP,Schmid H

更新日期：1993-03-01 00:00:00